Chimeric antigen receptor (CAR) redirected T cells are potent therapeutic options against hematological malignancies.The current dominant manufacturing approach for CAR T cells depends on retroviral transduction.With the advent of gene editing, insertion of a CD19-CAR into the T cell receptor (TCR) alpha constant (TRAC) locus using adeno-associated
The idea of building an artificial man extends through the entire history of mankind.In this paper we present a semi-anthropomimetic robot, as a structure that consists of an upper human-like body mounted on a cart (mobile platform).Semi-anthropomimetic robot uses the three-wheeled mobile platform (two driving wheels and one passive wheel).Upper bo
Summary: 1.Introduction: constitutional normality.2.Constitutional abnormality.2.1.The various possibilities in the face of extraordinary situations.2.1.1.The non-constitutionalization of extraordinary measures for State protection.2.1.2.The constitutional regulation of the concentration of powers.2.1.3.The detailed constitutionalization of one or
This Train Sets article focuses on the assessment of point clouds obtained by various laser scanning methods as a tool for 3D mapping and Digital Twin concepts.The presented research employed terrestrial and mobile laser scanning methods to obtain high-precision spatial data, enabling efficient spatial documentation of urban structures and infrastr